Structure of PDB 1ec6 Chain A

Receptor sequence
>1ec6A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
MKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRN
RRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV
3D structure
PDB1ec6 Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E14 N15 V17 G18 A19 L21 G22 K23 G24 Q40 I41 K43 K44 R54 R83 Q88 E11 N12 V14 G15 A16 L18 G19 K20 G21 Q37 I38 K40 K41 R51 R80 Q85
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1ec6, PDBe:1ec6, PDBj:1ec6
PDBsum1ec6
PubMed10676814
UniProtQ9UNW9|NOVA2_HUMAN RNA-binding protein Nova-2 (Gene Name=NOVA2)

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