Structure of PDB 1ea6 Chain A

Receptor sequence
>1ea6A (length=304) Species: 9606 (Homo sapiens) [Search protein sequence]
CSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVE
EENFEGLTLEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPY
PRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIR
VSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSD
SVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDP
AKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVLLQEEKLLLAVLKTSLI
GMFD
3D structure
PDB1ea6 Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N45 A49 L83 E109 L111 N19 A23 L57 E60 L62
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0030983 mismatched DNA binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0032300 mismatch repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ea6, PDBe:1ea6, PDBj:1ea6
PDBsum1ea6
PubMed11574484
UniProtP54278|PMS2_HUMAN Mismatch repair endonuclease PMS2 (Gene Name=PMS2)

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