Structure of PDB 1e6a Chain A

Receptor sequence
>1e6aA (length=284) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TYTTRQIGAKNTLEYKVYIEKDGKPVSAFHDIPLYADKENNIFNMVVEIP
RWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTW
EDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMALLDEGE
TDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPE
NQFAFSGEAKNKKYALDIIKETHDSWKQLIAGKSSDSKGIDLTNVTLPDT
PTYSKAASDAIPPASLKADAPIDKSIDKWFFISG
3D structure
PDB1e6a Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D115 D120 D152 D115 D120 D152
BS02 MN A D147 D152 D147 D152
BS03 POP A K56 E58 R78 Y93 D120 Y192 K193 K56 E58 R78 Y93 D120 Y192 K193
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphate phosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006796 phosphate-containing compound metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1e6a, PDBe:1e6a, PDBj:1e6a
PDBsum1e6a
PubMed11248042
UniProtP00817|IPYR_YEAST Inorganic pyrophosphatase (Gene Name=IPP1)

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