Structure of PDB 1e5j Chain A

Receptor sequence
>1e5jA (length=302) Species: 76935 (Salipaludibacillus agaradhaerens) [Search protein sequence]
SVVEEHGQLSISNGELVNERGEQVQLKGMSSHGLQWYGQFVNYESMKWLR
DDWGINVFRAAMYTSSGGYIDDPSVKEKVKEAVEAAIDLDIYVIIDWHIL
SDNDPNIYKEEAKDFFDEMSELYGDYPNVIYEIANEPNGSDVTWGNQIKP
YAEEVIPIIRNNDPNNIIIVGTGTWSQDVHHAADNQLADPNVMYAFHFYA
GTHGQNLRDQVDYALDQGAAIFVSEWGTSAATGDGGVFLDEAQVWIDFMD
ERNLSWANWSLTHKDESSAALMPGANPTGGWTEAELSPSGTFVREKIRES
AS
3D structure
PDB1e5j Mixed-Linkage Cellooligosaccharides: A New Class of Glycoside Hydrolase Inhibitors
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGC A E139 Y202 E136 Y199 PDBbind-CN: -logKd/Ki=4.00,Ki=100uM
BS02 SGC A H35 Y66 W262 K267 E269 H32 Y63 W259 K264 E266 PDBbind-CN: -logKd/Ki=4.00,Ki=100uM
BS03 GLC A W39 K267 W36 K264 PDBbind-CN: -logKd/Ki=4.00,Ki=100uM
BS04 CA A G127 D166 N168 N169 G124 D163 N165 N166
BS05 CA A D120 E124 D117 E121
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1e5j, PDBe:1e5j, PDBj:1e5j
PDBsum1e5j
PubMed11828460
UniProtO85465|GUN5_SALAG Endoglucanase 5A (Gene Name=cel5A)

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