Structure of PDB 1e3v Chain A

Receptor sequence
>1e3vA (length=128) Species: 303 (Pseudomonas putida) [Search protein sequence]
NLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVEDPFGQPPIHGRE
QIAAFYRQGLGGGKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDV
IDVMRFDEHGRIQTMQAYWSEVNLSVRE
3D structure
PDB1e3v Detection of Large Pka Perturbations of an Inhibitor and a Catalytic Group at an Enzyme Active Site, a Mechanistic Basis for Catalytic Power of Many Enzymes
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y16 D40 D100 D103
Catalytic site (residue number reindexed from 1) Y15 D39 D99 D102
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DXC A Y16 D40 Y57 G60 L99 D103 M116 Y15 D39 Y56 G59 L98 D102 M115 MOAD: Kd=45.74uM
PDBbind-CN: -logKd/Ki=4.34,Kd=45.74uM
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1e3v, PDBe:1e3v, PDBj:1e3v
PDBsum1e3v
PubMed11007792
UniProtP07445|SDIS_PSEPU Steroid Delta-isomerase (Gene Name=ksi)

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