Structure of PDB 1e3k Chain A

Receptor sequence
>1e3kA (length=251) Species: 9606 (Homo sapiens) [Search protein sequence]
QLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVK
WSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPD
LILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIP
LEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLH
DLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFH
K
3D structure
PDB1e3k Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R18 A L718 N719 L721 Q725 M759 F778 C891 L37 N38 L40 Q44 M78 F97 C210 BindingDB: Ki=0.490000nM
External links
PDB RCSB:1e3k, PDBe:1e3k, PDBj:1e3k
PDBsum1e3k
PubMed10840043
UniProtP06401|PRGR_HUMAN Progesterone receptor (Gene Name=PGR)

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