Structure of PDB 1e12 Chain A

Receptor sequence
>1e12A (length=239) Species: 2242 (Halobacterium salinarum) [Search protein sequence]
RENALLSSSLWVNVALAGIAILVFVYMGRTIRPGRPRLIWGATLMIPLVS
ISSYLGLLSGLTVGMIEMPAGHALAGEMVRSQWGRYLTWALSTPMILLAL
GLLADVDLGSLFTVIAADIGMCVTGLAAAMTTSALLFRWAFYAISCAFFV
VVLSALVTDWAASASSAGTAEIFDTLRVLTVVLWLGYPIVWAVGVEGLAL
VQSVGATSWAYSVLDVFAKYVFAFILLRWVANNERTVAV
3D structure
PDB1e12 Structure of Light-Driven Chloride Pump Halorhodopsin at 1.8 A Resolution
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CL A T111 S115 K242 T88 S92 K219
BS02 PLM A F135 V146 F112 V123
BS03 RET A W112 T116 M144 S168 F172 W207 Y210 P211 K242 W89 T93 M121 S145 F149 W184 Y187 P188 K219
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0009881 photoreceptor activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0007602 phototransduction
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:1e12, PDBe:1e12, PDBj:1e12
PDBsum1e12
PubMed10827943
UniProtP0DMH7|BACH_HALSA Halorhodopsin (Gene Name=hop)

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