Structure of PDB 1du0 Chain A

Receptor sequence
>1du0A (length=53) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
AFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFANKRAKI
KKS
3D structure
PDB1du0 Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A F8 Q44 I47 N51 F2 Q38 I41 N45 PDBbind-CN: Kd=79pM
BS02 dna A Y25 R53 K57 Y19 R47 K51 PDBbind-CN: Kd=79pM
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1du0, PDBe:1du0, PDBj:1du0
PDBsum1du0
PubMed10889025
UniProtP02836|HMEN_DROME Segmentation polarity homeobox protein engrailed (Gene Name=en)

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