Structure of PDB 1ds4 Chain A

Receptor sequence
>1ds4A (length=292) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TLVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWH
ISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWI
SSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAG
YVRTFFQRLNMNDREVVALMGAGALGKTHLKNSGYEGPWGAANNVFTNEF
YLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYA
NDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL
3D structure
PDB1ds4 Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure.
ChainA
Resolution2.02 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R48 H52 G175 W191 D235
Catalytic site (residue number reindexed from 1) R46 H50 G173 W189 D233
Enzyme Commision number 1.11.1.5: cytochrome-c peroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A R48 W51 P145 D146 A147 M172 G178 K179 T180 H181 N184 S185 W191 L232 R46 W49 P143 D144 A145 M170 G176 K177 T178 H179 N182 S183 W189 L230
BS02 IMD A M172 W191 D235 M170 W189 D233
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
Biological Process
GO:0006979 response to oxidative stress
GO:0034599 cellular response to oxidative stress

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Molecular Function
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Biological Process
External links
PDB RCSB:1ds4, PDBe:1ds4, PDBj:1ds4
PDBsum1ds4
PubMed11170452
UniProtP00431|CCPR_YEAST Cytochrome c peroxidase, mitochondrial (Gene Name=CCP1)

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