Structure of PDB 1dnp Chain A

Receptor sequence
>1dnpA (length=469) Species: 562 (Escherichia coli) [Search protein sequence]
TTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQ
AELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLF
YNYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVF
TPFKNAWLKRLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHF
PVEEKAAIAQLRQFCQNGAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQ
CLHRLLAEQPQALDGGAGSVWLNELIWREFYRHLITYHPSLCKHRPFIAW
TDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLRMITASF
LVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFN
PTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQPI
VEHKEARVQTLAAYEAARK
3D structure
PDB1dnp Crystal structure of DNA photolyase from Escherichia coli.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E274 W277 W306 N341 W359 W382
Catalytic site (residue number reindexed from 1) E274 W277 W306 N341 W359 W382
Enzyme Commision number 4.1.99.3: deoxyribodipyrimidine photo-lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A Y222 T234 S235 R236 L237 S238 W271 E274 R278 Y281 W338 N341 R344 D372 A377 N378 G381 W382 Y222 T234 S235 R236 L237 S238 W271 E274 R278 Y281 W338 N341 R344 D372 A377 N378 G381 W382
BS02 MHF A H44 N108 E109 C292 K293 H44 N108 E109 C292 K293
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003904 deoxyribodipyrimidine photo-lyase activity
GO:0005515 protein binding
GO:0016829 lyase activity
GO:0071949 FAD binding
GO:0097159 organic cyclic compound binding
Biological Process
GO:0000719 photoreactive repair
GO:0006139 nucleobase-containing compound metabolic process
GO:0006281 DNA repair
GO:0006950 response to stress
GO:0007603 phototransduction, visible light
GO:0009416 response to light stimulus

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Molecular Function
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Biological Process
External links
PDB RCSB:1dnp, PDBe:1dnp, PDBj:1dnp
PDBsum1dnp
PubMed7604260
UniProtP00914|PHR_ECOLI Deoxyribodipyrimidine photo-lyase (Gene Name=phrB)

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