Structure of PDB 1dl5 Chain A

Receptor sequence
>1dl5A (length=317) Species: 2336 (Thermotoga maritima) [Search protein sequence]
MREKLFWILKKYGVSDHIAKAFLEIPREEFLTKSYPLSYVYEDIVLVSYD
DGEEYSTSSQPSLMALFMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEK
GLVVSVEYSRKICEIAKRNVERLGIENVIFVCGDGYYGVPEFSPYDVIFV
TVGVDEVPETWFTQLKEGGRVIVPINLKLSRRQPAFLFKKKDPYLVGNYK
LETRFITAGGNLGNLLERNRKLLREFPFNREILLVRSHIFVELVDLLTRR
LTEIDGTFYYAGPNGVVEFLDDRMRIYGDAPEIENLLTQWESCGYRSFEY
LMLHVGYNAFSHISCSI
3D structure
PDB1dl5 Crystal structure of protein isoaspartyl methyltransferase: a catalyst for protein repair.
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S59
Catalytic site (residue number reindexed from 1) S59
Enzyme Commision number 2.1.1.77: protein-L-isoaspartate(D-aspartate) O-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A S56 T57 E81 G83 G84 G85 N89 E107 Y108 D134 G135 T151 V152 A208 G209 S56 T57 E81 G83 G84 G85 N89 E107 Y108 D134 G135 T151 V152 A208 G209
Gene Ontology
Molecular Function
GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0030091 protein repair
GO:0032259 methylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1dl5, PDBe:1dl5, PDBj:1dl5
PDBsum1dl5
PubMed11080641
UniProtQ56308|PIMT_THEMA Protein-L-isoaspartate O-methyltransferase (Gene Name=pcm)

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