Structure of PDB 1djl Chain A

Receptor sequence
>1djlA (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
PMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKML
TEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTD
LVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAA
VDNPIFYKPNTAMLLGDAKKTCDALQAKVRES
3D structure
PDB1djl The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y890 R925 D967 Y1006
Catalytic site (residue number reindexed from 1) Y32 R67 D109 Y148
Enzyme Commision number 7.1.1.1: proton-translocating NAD(P)(+) transhydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G889 Y890 G891 V922 A923 G924 R925 M926 P927 G964 A965 N966 D967 T968 K999 R1000 S1001 V1004 G1005 Y1006 D1025 A1026 G31 Y32 G33 V64 A65 G66 R67 M68 P69 G106 A107 N108 D109 T110 K141 R142 S143 V146 G147 Y148 D167 A168
External links
PDB RCSB:1djl, PDBe:1djl, PDBj:1djl
PDBsum1djl
PubMed10673423
UniProtQ13423|NNTM_HUMAN NAD(P) transhydrogenase, mitochondrial (Gene Name=NNT)

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