Structure of PDB 1dgj Chain A

Receptor sequence

>1dgjA (length=906) Species: 876 (Desulfovibrio desulfuricans)

METKTLIVNGMARRLLVSPNDLLVDVLRSQLQLTSVKVGCGKGQCGACTV
ILDGKVVRACIIKMSRVAENASVTTLEGIGAPDCLHPLQHAWIQHGAAQC
GFCTPGFIVSAKALLDENVAPSREDVRDWFQKHHNICRCTGYKPLVDAVM
DAAAILRGEKTVEEISFKMPADGRIWGSSIPRPSAVAKVTGLAEFGADAA
LRMPENTLHLALAQAKVSHALIKGIDTSEAEKMPGVYKVLTHKDVKGKNR
ITGLITFPTNKGDGWERPILNDSKIFQYGDALAIVCADSEANARAAAEKV
KFDLELLPEYMSAPEAMAPDAIEIHPGTPNVYYDQLEEKGEDTVPFFNDP
ANVVAEGSYYTQRQPHLPIEPDVGYGYINEQGQVVIHSKSVAIHLHALMI
APGLGLEFPKDLVLVQNTTGGTFGYKFSPTMEALVGVAVMATGRPCHLRY
NYEQQQNYTGKRSPFWTTMRYAADRQGKILAMETDWSVDHGPYSEFGDLL
TLRGAQYIGAGYGIANIRGTGRTVATNHCWGAAFRGYGAPESEFPSEVLM
DELAEKLGMDPFELRALNCYREGDTTSSGQIPEVMSLPEMFDKMRPYYEE
SKKRVKERSTAEIKRGVGVALGVYGAGLDGPDTSEAWVELNDDGSVTLGN
SWEDHGQGADAGSLGTAHEALRPLGITPENIHLVMNDTSKTPNSGPAGGS
RSQVVTGNAIRVACEMLIEGMRKPGGGFFTPAEMKAEGRPMRYDGKWTAP
AKDCDAKGQGSPFACYMYGLFLTEVAVEVATGKATVEKMVCVADIGKICN
KLVVDGQIYGGLAQGVGLALSEDYEDLKKHSTMGGAGIPSIKMIPDDIEI
VYVETPRKDGPFGASGVGEMPLTAPHAAIINGIYNACGARVRHLPARPEK
VLEAMP

3D structure

• PDB: 1dgj Gene sequence and crystal structure of the aldehyde oxidoreductase from Desulfovibrio desulfuricans ATCC 27774.
• Chain: A
• Resolution: 2.8 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): V391 F427 R503 Y507 R535 E869 M870
• Catalytic site (residue number reindexed from 1): V391 F427 R503 Y507 R535 E869 M870
• Enzyme Commision number: 1.2.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FES	A	C100 G101 C103 C137 C139	C100 G101 C103 C137 C139
BS02	FES	A	V38 G39 C40 G41 G43 Q44 C45 G46 C48 R58 C60	V38 G39 C40 G41 G43 Q44 C45 G46 C48 R58 C60
BS03	2MO	A	G424 R535 G698 E869	G424 R535 G698 E869
BS04	MCN	A	Q99 C139 F423 G424 R535 W652 H655 G656 Q657 G658 A697 G698 S700 S702 Q703 C799 N800 V803 V804 Q807 S865 G866 V867 G868 E869	Q99 C139 F423 G424 R535 W652 H655 G656 Q657 G658 A697 G698 S700 S702 Q703 C799 N800 V803 V804 Q807 S865 G866 V867 G868 E869

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051536 iron-sulfur cluster binding
• GO:0051537 2 iron, 2 sulfur cluster binding

External links

• PDB: RCSB:1dgj, PDBe:1dgj, PDBj:1dgj
• PDBsum: 1dgj
• PubMed: 10704312
• UniProt: Q9REC4