Structure of PDB 1ddi Chain A

Receptor sequence

>1ddiA (length=374) Species: 562 (Escherichia coli) [Search protein sequence]

IHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDA
LGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNT
ANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEA
LINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFL
ADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRA
ADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEK
VYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGG
MDTEAADEFLSELRVERRYQRDVY

3D structure

PDB

1ddi Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module.

Chain

Resolution

2.51 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	Y388 S389 C552 D597 Y599
Catalytic site (residue number reindexed from 1)	Y163 S164 C327 D372 Y374
Enzyme Commision number	1.8.1.2: assimilatory sulfite reductase (NADPH).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	T322 V323 A356 T357 R386 L387 Y388 S389 T404 V405 Y410 G419 G420 A421 S422 T462 Y599	T97 V98 A131 T132 R161 L162 Y163 S164 T179 V180 Y185 G194 G195 A196 S197 T237 Y374
BS02	NAP	A	P460 G461 N489 S519 R520 Y527 Q529 M558 D561	P235 G236 N264 S294 R295 Y302 Q304 M333 D336

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:1ddi, PDBe:1ddi, PDBj:1ddi
PDBsum	1ddi
PubMed	10860732
UniProt	P38038\|CYSJ_ECOLI Sulfite reductase [NADPH] flavoprotein alpha-component (Gene Name=cysJ)

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