Structure of PDB 1d2s Chain A

Receptor sequence
>1d2sA (length=170) Species: 9606 (Homo sapiens) [Search protein sequence]
PPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNP
KDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSV
LLEVDGEEVLRLRQVSGHPIMRIALGGLLFPASNLRLPLVPALDGCLRRD
SWLDKQAEISASAPTSLRSC
3D structure
PDB1d2s Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D50 E52 A160 D38 E40 A142
BS02 DHT A S41 S42 D65 F67 N82 L171 S29 S30 D53 F55 N70 L153 PDBbind-CN: -logKd/Ki=9.74,Kd=0.182nM
BindingDB: IC50=3.8nM,Kd=0.182000nM
External links
PDB RCSB:1d2s, PDBe:1d2s, PDBj:1d2s
PDBsum1d2s
PubMed10675319
UniProtP04278|SHBG_HUMAN Sex hormone-binding globulin (Gene Name=SHBG)

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