Structure of PDB 1d1q Chain A

Receptor sequence
>1d1qA (length=159) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
IEKPKISVAFIALGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNY
HVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNL
KKIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEYNFKQITYF
SKQFLKKEL
3D structure
PDB1d1q Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A13 N16 C18 R19 S20 D132
Catalytic site (residue number reindexed from 1) A12 N15 C17 R18 S19 D131
Enzyme Commision number 3.1.3.2: acid phosphatase.
3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4NP A A13 L14 G15 N16 F17 C18 R19 D132 W134 A12 L13 G14 N15 F16 C17 R18 D131 W133
Gene Ontology
Molecular Function
GO:0003993 acid phosphatase activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1d1q, PDBe:1d1q, PDBj:1d1q
PDBsum1d1q
PubMed10684639
UniProtP40347|PPAL_YEAST Low molecular weight phosphotyrosine protein phosphatase (Gene Name=LTP1)

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