Structure of PDB 1cyf Chain A

Receptor sequence
>1cyfA (length=296) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MITTPLVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVR
LAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKE
FPWISSGDLFSLGGVTAVQEMQGPKIPWRAGRVDTPEDTTPDNGRLPDAD
KDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPWGCANNVF
TNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIV
KEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL
3D structure
PDB1cyf Identifying the physiological electron transfer site of cytochrome c peroxidase by structure-based engineering.
ChainA
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R48 H52 H175 W191 D235
Catalytic site (residue number reindexed from 1) R50 H54 H177 W193 D237
Enzyme Commision number 1.11.1.5: cytochrome-c peroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A R48 W51 P145 D146 M172 A174 H175 L177 G178 H181 N184 S185 W191 L232 R50 W53 P147 D148 M174 A176 H177 L179 G180 H183 N186 S187 W193 L234
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
Biological Process
GO:0006979 response to oxidative stress
GO:0034599 cellular response to oxidative stress

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Molecular Function
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Biological Process
External links
PDB RCSB:1cyf, PDBe:1cyf, PDBj:1cyf
PDBsum1cyf
PubMed8547245
UniProtP00431|CCPR_YEAST Cytochrome c peroxidase, mitochondrial (Gene Name=CCP1)

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