Structure of PDB 1cx4 Chain A

Receptor sequence
>1cx4A (length=275) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHV
IDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP
RAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLE
VSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRNGAV
EIARCLRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCM
EIMKRNIATYEEQLVALFGTNMDIV
3D structure
PDB1cx4 Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A I199 Y213 F219 G220 E221 L222 A223 R230 A231 R381 I70 Y84 F90 G91 E92 L93 A94 R101 A102 R244
BS02 CMP A I339 F348 G349 E350 L351 A352 R359 A360 A361 Y397 I202 F211 G212 E213 L214 A215 R222 A223 A224 Y260
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1cx4, PDBe:1cx4, PDBj:1cx4
PDBsum1cx4
PubMed11342137
UniProtP12369|KAP3_RAT cAMP-dependent protein kinase type II-beta regulatory subunit (Gene Name=Prkar2b)

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