Structure of PDB 1csy Chain A

Receptor sequence
>1csyA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
GSRRASVGSHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSY
ALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR
VLTVPCQKIGTQ
3D structure
PDB1csy Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R22 A51 L61 H62 Y63 R64 I75 E77 G78 G97 L98 R22 A51 L61 H62 Y63 R64 I75 E77 G78 G97 L98
External links
PDB RCSB:1csy, PDBe:1csy, PDBj:1csy
PDBsum1csy
PubMed8590001
UniProtP43405|KSYK_HUMAN Tyrosine-protein kinase SYK (Gene Name=SYK)

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