Structure of PDB 1csw Chain A

Receptor sequence

>1cswA (length=108) Species: 4932 (Saccharomyces cerevisiae)

TEFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEG
YSYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGMKKEKDRNDLI
TYLKKATE

3D structure

• PDB: 1csw Replacements in a conserved leucine cluster in the hydrophobic heme pocket of cytochrome c.
• Chain: A
• Resolution: 1.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	R13 C14 C17 H18 G29 L32 I35 S40 Y46 Y48 T49 N52 W59 M64 Y67 T78 K79 M80 F82	R18 C19 C22 H23 G34 L37 I40 S45 Y51 Y53 T54 N57 W64 M69 Y72 T83 K84 M85 F87

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:1csw, PDBe:1csw, PDBj:1csw
• PDBsum: 1csw
• PubMed: 7757009
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)