Structure of PDB 1cr4 Chain A

Receptor sequence
>1cr4A (length=243) Species: 10760 (Escherichia phage T7) [Search protein sequence]
MRERIREHLSSEESVGLLFSGCTGINDKTLGARGGEVIMVTSGSGMGKST
FVRQQALQWGTAMGKKVGLAMLEESVEETAEDLIGLHNRVRLRQSDSLKR
EIIENGKFDQWFDELFGNDTFHLYDSFAEAETDRLLAKLAYMRSGLGCDV
IILDHISIRKMIDNLMTKLKGFAKSTGVVLVVICHLKDLRGGALRQLSDT
IIALERNQLVLVRILKCRFTGDTGIAGYMEYNKETGWLEPSSY
3D structure
PDB1cr4 Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
3.6.4.12: DNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 TYD A G315 M316 G317 K318 S319 T320 R504 Y535 G45 M46 G47 K48 S49 T50 R206 Y231
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0006260 DNA replication

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Molecular Function

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Biological Process
External links
PDB RCSB:1cr4, PDBe:1cr4, PDBj:1cr4
PDBsum1cr4
PubMed10535735
UniProtP03692|HELIC_BPT7 DNA helicase/primase (Gene Name=4)

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