Structure of PDB 1cqw Chain A

Receptor sequence
>1cqwA (length=295) Species: 1831 (Rhodococcus sp. (in: high G+C Gram-positive bacteria)) [Search protein sequence]
IGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNIIP
HVAPSHRCIAPDLIGMGKSDKPDLDYFFDDHVRYLDAFIEALGLEEVVLV
IHDWGSALGFHWAKRNPERVKGIACMEFIRPIPTWDEWPEFARETFQAFR
TADVGRELIIDQNAFIEGVLPKCVVRPLTEVEMDHYREPFLKPVDREPLW
RFPNEIPIAGEPANIVALVEAYMNWLHQSPVPKLLFWGTPGVLIPPAEAA
RLAESLPNCKTVDIGPGLHYLQEDNPDLIGSEIARWLPGLASGLG
3D structure
PDB1cqw Haloalkane dehalogenases: structure of a Rhodococcus enzyme.
ChainA
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N52 D117 W118 E141 W152 T159 P217 G255 H283
Catalytic site (residue number reindexed from 1) N38 D103 W104 E127 W138 T145 P203 G241 H269
Enzyme Commision number 3.8.1.5: haloalkane dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IOD A W118 F216 P217 I220 W104 F202 P203 I206
BS02 IOD A C187 H283 C173 H269
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018786 haloalkane dehalogenase activity

View graph for
Molecular Function
External links
PDB RCSB:1cqw, PDBe:1cqw, PDBj:1cqw
PDBsum1cqw
PubMed10587433
UniProtP59336|DHAA_RHOSD Haloalkane dehalogenase (Gene Name=dhaA)

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