Structure of PDB 1cpo Chain A

Receptor sequence

>1cpoA (length=299) Species: 5474 (Leptoxyphium fumago) [Search protein sequence]

QEPGSGIGYPYDNNTLPYVAPGPTDSRAPCPALNALANHGYIPHDGRAIS
RETLQNAFLNHMGIANSVIELALTNAFVVCEYVTGSDCGDSLVNLTLLAE
PHAFEHDHSFSRKDYKQGVANSNDFIDNRNFDAETFQTSLDVVAGKTHFD
YADMNEIRLQRESLSNELDFPGWFTESKPIQNVESGFIFALVSDFNLPDN
DENPLVRIDWWKYWFTNESFPYHLGWHPPSPAREIEFVTSASSAVLAASV
TSTPSSLPSGAIGPGAEAVPLSFASTMTPFLLATNAPYYAQDPTLGPND

3D structure

PDB

1cpo The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 functional hybrid.

Chain

Resolution

1.9 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	C29 H105 D106 E183
Catalytic site (residue number reindexed from 1)	C30 H106 D107 E184
Enzyme Commision number	1.11.1.10: chloride peroxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	MAN	A	A273 T275	A274 T276
BS02	MAN	A	E235 T238 E266	E236 T239 E267
BS03	MAN	A	Y150 D200 E201 F236 S239	Y151 D201 E202 F237 S240
BS04	MAN	A	P178 N181 S241 L245 G264 A265	P179 N182 S242 L246 G265 A266
BS05	MAN	A	A151 D152 T250	A152 D153 T251
BS06	MAN	A	Q159 S251 P253	Q160 S252 P254
BS07	MAN	A	V249 T252 I261	V250 T253 I262
BS08	MN	A	E104 H105 S108	E105 H106 S109
BS09	HEM	A	P28 C29 P30 A31 L32 F57 I68 A71 F103 E104 H105 S108 F109 S110 E183 F186	P29 C30 P31 A32 L33 F58 I69 A72 F104 E105 H106 S109 F110 S111 E184 F187

Gene Ontology

	Molecular Function
GO:0004601	peroxidase activity

View graph for
Molecular Function

External links

PDB	RCSB:1cpo, PDBe:1cpo, PDBj:1cpo
PDBsum	1cpo
PubMed	8747463
UniProt	P04963\|PRXC_LEPFU Chloroperoxidase (Gene Name=CPO)

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