Structure of PDB 1cka Chain A

Receptor sequence
>1ckaA (length=57) Species: 10090 (Mus musculus) [Search protein sequence]
AEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIP
VPYVEKY
3D structure
PDB1cka Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F141 D147 E149 D150 E166 Q168 W169 P183 P185 Y186 F8 D14 E16 D17 E33 Q35 W36 P50 P52 Y53
External links
PDB RCSB:1cka, PDBe:1cka, PDBj:1cka
PDBsum1cka
PubMed7735837
UniProtQ64010|CRK_MOUSE Adapter molecule crk (Gene Name=Crk)

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