Structure of PDB 1ci9 Chain A

Receptor sequence
>1ci9A (length=377) Species: 28095 (Burkholderia gladioli) [Search protein sequence]
AASLAARLDAVFDQALRERRLVGAVAIVARHGEILYRRAQGLADREAGRP
MREDTLFRLASVTKPIVALAVLRLVARGELALDAPVTRWLPEFRPRLADG
SEPLVTIHHLLTHTSGLGYWLLEGAGSVYDRLGISDGIDLRDFDLDENLR
RLASAPLSFAPGSGWQYSLALDVLGAVVERATGQPLAAAVDALVAQPLGM
RDCGFVSAEPERFAVPYHDGQPEPVRMRDGIEVPLPEGHGAAVRFAPSRV
FEPGAYPSGGAGMYGSADDVLRALEAIRANPGFLPETLADAARRDQAGVG
AETRGPGWGFGYLSAVLDDPAAAGTPQHAGTLQWGGVYGHSWFVDRALGL
SVLLLTNTAYEGMSGPLTIALRDAVYA
3D structure
PDB1ci9 EstB from Burkholderia gladioli: a novel esterase with a beta-lactamase fold reveals steric factors to discriminate between esterolytic and beta-lactam cleaving activity
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S75 K78 Y133 L135 I152 Y181 L183 D186 H253 W348 V351
Catalytic site (residue number reindexed from 1) S61 K64 Y119 L121 I138 Y167 L169 D172 H239 W334 V337
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DFP A A74 S75 Y181 W348 G350 V351 A60 S61 Y167 W334 G336 V337
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ci9, PDBe:1ci9, PDBj:1ci9
PDBsum1ci9
PubMed11847270
UniProtQ9KX40|ESTB_BURGA Esterase EstB (Gene Name=estB)

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