Structure of PDB 1cgz Chain A

Receptor sequence
>1cgzA (length=387) Species: 3879 (Medicago sativa) [Search protein sequence]
SVSEIRKAQRAEGPATILAIGTANPANCVEQSTYPDFYFKITNSEHKTEL
KEKFQRMCDKSMIKRRYMYLTEEILKENPNVCEYMAPSLDARQDMVVVEV
PRLGKEAAVKAIKEWGQPKSKITHLIVCTTSGVDMPGADYQLTKLLGLRP
YVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPS
DTHLDSLVGQALFGDGAAALIVGSDPVPEIEKPIFEMVWTAQTIAPDSEG
AIDGHLREAGLTFHLLKDVPGIVSKNITKALVEAFEPLGISDYNSIFWIA
HPGGPAILDQVEQKLALKPEKMNATREVLSEYGNMSSACVLFILDEMRKK
STQNGLKTTGEGLEWGVLFGFGPGLTIETVVLRSVAI
3D structure
PDB1cgz Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C164 F215 H303 N336
Catalytic site (residue number reindexed from 1) C162 F213 H301 N334
Enzyme Commision number 2.3.1.74: chalcone synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 STL A E192 V193 T194 T197 F215 G216 I254 D255 T264 F265 S338 P375 E190 V191 T192 T195 F213 G214 I252 D253 T262 F263 S336 P373
Gene Ontology
Molecular Function
GO:0016210 naringenin-chalcone synthase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0009058 biosynthetic process
GO:0009715 chalcone biosynthetic process
GO:0009813 flavonoid biosynthetic process
GO:0030639 polyketide biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1cgz, PDBe:1cgz, PDBj:1cgz
PDBsum1cgz
PubMed10426957
UniProtP30074|CHS2_MEDSA Chalcone synthase 2 (Gene Name=CHS2)

[Back to BioLiP]