Structure of PDB 1cgu Chain A

Receptor sequence
>1cguA (length=684) Species: 1397 (Niallia circulans) [Search protein sequence]
DPDTAVTNKQSFSTDVIYQVFTDRFLDGNPSNNPTGAAYDATCSNLKLYC
GGDWQGLINKINDNYFSDLGVTALWISQPVENIFATINYSGVTNTAYHGY
WARDFKKTNPYFGTMADFQNLITTAHAKGIKIVIDFAPNHTSPAMETDTS
FAENGRLYDNGTLVGGYTNDTNGYFHHNGGSDFSSLENGIYKNLYDLADF
NHNNATIDKYFKDAIKLWLDMGVDGIRVAAVKHMPLGWQKSWMSSIYAHK
PVFTFGEWFLGSAASDADNTDFANKSGMSLLDFRFNSAVRNVFRDNTSNM
YALDSMINSTATDYNQVNDQVTFIDNHDMDRFKTSAVNNRRLEQALAFTL
TSRGVPAIYYGTEQYLTGNGDPDNRAKMPSFSKSTTAFNVISKLAPLRKS
NPAIAYGSTQQRWINNDVYVYERKFGKSVAVVAVNRNLSTSASITGLSTS
LPTGSYTDVLGGVLNGNNITSTNGSINNFTLAAGATAVWQYTTAETTPTI
GHVGPVMGKPGNVVTIDGRGFGSTKGTVYFGTTAVTGAAITSWEDTQIKV
TIPSVAAGNYAVKVAASGVNSNAYNNFTILTGDQVTVRFVVNNASTTLGQ
NLYLTGNVAELGNWSTGSTAIGPAFNQVIHQYPTWYYDVSVPAGKQLEFK
FFKKNGSTITWESGSNHTFTTPASGTATVTVNWQ
3D structure
PDB1cgu Catalytic center of cyclodextrin glycosyltransferase derived from X-ray structure analysis combined with site-directed mutagenesis.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D135 R227 A229 E257 H327 D328
Catalytic site (residue number reindexed from 1) D135 R227 A229 E257 H327 D328
Enzyme Commision number 2.4.1.19: cyclomaltodextrin glucanotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A Y100 H140 E257 H327 D328 Y100 H140 E257 H327 D328
BS02 GLC A Y100 W101 D371 R375 Y100 W101 D371 R375
BS03 CA A N139 I190 D199 H233 N139 I190 D199 H233
BS04 CA A D27 N29 N32 N33 G51 D53 D27 N29 N32 N33 G51 D53
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004556 alpha-amylase activity
GO:0016757 glycosyltransferase activity
GO:0030246 carbohydrate binding
GO:0043169 cation binding
GO:0043895 cyclomaltodextrin glucanotransferase activity
GO:0046872 metal ion binding
GO:2001070 starch binding
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1cgu, PDBe:1cgu, PDBj:1cgu
PDBsum1cgu
PubMed1390660
UniProtP30920|CDGT1_NIACI Cyclomaltodextrin glucanotransferase

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