Structure of PDB 1cff Chain A

Receptor sequence

>1cffA (length=148) Species: 8355 (Xenopus laevis)

ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD
MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI
SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

3D structure

• PDB: 1cff NMR solution structure of a complex of calmodulin with a binding peptide of the Ca2+ pump.
• Chain: A
• Resolution: N/A

Enzymatic activity

• Catalytic site (original residue number in PDB): V35
• Catalytic site (residue number reindexed from 1): V35

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	A88 F92 I100 L105 M109 L112 M124 E127 F141 M144 M145	A88 F92 I100 L105 M109 L112 M124 E127 F141 M144 M145
BS02	CA	A	D20 D22 D24 T26 E31	D20 D22 D24 T26 E31
BS03	CA	A	D56 D58 G59 N60 T62 E67	D56 D58 G59 N60 T62 E67
BS04	CA	A	D93 D95 N97 Y99 E104	D93 D95 N97 Y99 E104
BS05	CA	A	D129 D131 D133 Q135 V136 E140	D129 D131 D133 Q135 V136 E140

Gene Ontology

Molecular Function

• GO:0005102 signaling receptor binding
• GO:0005509 calcium ion binding
• GO:0030234 enzyme regulator activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:1cff, PDBe:1cff, PDBj:1cff
• PDBsum: 1cff
• PubMed: 10493800
• UniProt: P0DP33|CALM1_XENLA Calmodulin-1 (Gene Name=calm1)