Structure of PDB 1cbf Chain A

Receptor sequence
>1cbfA (length=239) Species: 1404 (Priestia megaterium) [Search protein sequence]
GLVPRGSHMKLYIIGAGPGDPDLITVKGLKLLQQADVVLYADSLVSQDLI
AKSKPGAEVLKTAGMHLEEMVGTMLDRMREGKMVVRVHTGDPAMYGAIME
QMVLLKREGVDIEIVPGVTSVFAAAAAAEAELTIPDLTQTVILTRAEGRT
PVPEFEKLTDLAKHKCTIALFLSSTLTKKVMKEFINAGWSEDTPVVVVYK
ATWPDEKIVRTTVKDLDDAMRTNGIRKQAMILAGWALDP
3D structure
PDB1cbf The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase.
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D54 L184
Catalytic site (residue number reindexed from 1) D42 L172
Enzyme Commision number 2.1.1.271: cobalt-precorrin-4 methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A T101 G102 D103 M106 T131 S132 F183 L184 K212 A213 Q240 A241 M242 T89 G90 D91 M94 T119 S120 F171 L172 K200 A201 Q228 A229 M230
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0046026 precorrin-4 C11-methyltransferase activity
Biological Process
GO:0009236 cobalamin biosynthetic process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1cbf, PDBe:1cbf, PDBj:1cbf
PDBsum1cbf
PubMed9665173
UniProtO87696|CBIF_PRIMG Cobalt-precorrin-4 C(11)-methyltransferase (Gene Name=cbiF)

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