Structure of PDB 1c4k Chain A

Receptor sequence
>1c4kA (length=728) Species: 1593 (Lactobacillus sp. 30A) [Search protein sequence]
SSSLKIASTQEARQYFDTDRVVVDAVGSDFTDVGAVIAMDYETDVIDAAD
ATKFGIPVFAVTKDAQAISADELKKIFHIIDLEFDATVNAREIETAVNNY
EDSILPPFFKSLKEYVSRYLIQFDCPGHQGGQYYRKHPAGREFYDFFGET
VFRADLCNADVALGDLLIHEGPAVAAEKHAARVYNADKTYFVLGGSSNAN
NTVTSALVSNGDLVLFDRNNHKSVYNSALAMAGGRPVYLQTNRNPYGFIG
GIYDSDFDEKKIRELAAKVDPERAKWKRPFRLAVIQLGTYDGTIYNAHEV
VKRIGHLCDYIEFDSAWVGYEQFIPMMRNSSPLLIDDLGPEDPGIIVVQS
VHKQQAGFSQTSQIHKKDSHIKGQLRYCDHKHFNNSFNLFMSTSPFYPMY
AALDVNAAMQEGEAGRKLWHDLLITTIEARKKLIKAGSMFRPFVPPVVNG
KKWEDGDTEDMANNIDYWRFEKGAKWHAYEGYGDNQYYVDPNKFMLTTPG
INPETGDYEDFGVPATIVANYLRDHGIIPEKSDLNSILFLMTPAETPAKM
NNLITQLLQLQRLIEEDAPLKQVLPSIYAANEERYNGYTIRELCQELHDF
YKNNNTFTYQKRLFLREFFPEQGMLPYEARQEFIRNHNKLVPLNKIEGEI
ALEGALPYPPGVFCVAPGEKWSETAVKYFTILQDGINNFPGFAPEIQGVY
FKQEGDKVVAYGEVYDAEVAKNDDRYNN
3D structure
PDB1c4k Three-dimensional structure of the Gly121Tyr dimeric form of ornithine decarboxylase from Lactobacillus 30a.
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H223 D316 K355
Catalytic site (residue number reindexed from 1) H221 D314 K353
Enzyme Commision number 4.1.1.17: ornithine decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A G197 S198 S199 H223 D316 A318 S352 H354 K355 G195 S196 S197 H221 D314 A316 S350 H352 K353
BS02 GTP A H171 E179 K190 T191 Y192 K374 Y379 D381 H382 K383 H169 E177 K188 T189 Y190 K372 Y377 D379 H380 K381
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004586 ornithine decarboxylase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006520 amino acid metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1c4k, PDBe:1c4k, PDBj:1c4k
PDBsum1c4k
PubMed10666573
UniProtP43099|DCOR_LACS3 Inducible ornithine decarboxylase (Gene Name=odcI)

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