Structure of PDB 1c47 Chain A

Receptor sequence
>1c47A (length=561) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
VKIVTVKTKAYPDQKPGTSGLRKRVKVFQSSTNYAENFIQSIISTVEPAQ
RQEATLVVGGDGRFYMKEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSC
IIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQIS
KTIEEYAICPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRN
IFDFNALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNC
VPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHG
FFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIA
LYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSI
LATRKQSVEDILKDHWHKFGRNFFTRYDYEEVEAEGATKMMKDLEALMFD
RSFVGKQFSANDKVYTVEKADNFEYHDPVDGSVSKNQGLRLIFADGSRII
FRLSGTGSAGATIRLYIDSYEKDNAKINQDPQVMLAPLISIALKVSQLQE
RTGRTAPTVIT
3D structure
PDB1c47 ENHANCED DIFFRACTIVITY OF PHOSPHOGLUCOMUTASE CRYSTALS - USE OF AN ALTERNATE CRYOCRYSTALLOGRAPHIC PROCEDURE
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R22 S116 H117 K129 D287 D289 D291 R292 G379 K388
Catalytic site (residue number reindexed from 1) R22 S116 H117 K129 D287 D289 D291 R292 G379 K388
Enzyme Commision number 5.4.2.2: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G16 A R22 S116 D291 R292 E375 K388 R22 S116 D291 R292 E375 K388
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004614 phosphoglucomutase activity
GO:0016853 isomerase activity
GO:0016868 intramolecular phosphotransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016529 sarcoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1c47, PDBe:1c47, PDBj:1c47
PDBsum1c47
PubMed
UniProtP00949|PGM1_RABIT Phosphoglucomutase-1 (Gene Name=PGM1)

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