Structure of PDB 1c1x Chain A

Receptor sequence
>1c1xA (length=348) Species: 1831 (Rhodococcus sp. (in: high G+C Gram-positive bacteria)) [Search protein sequence]
SIDSALNWDGEMTVTRFDSMTGAHFVIRLDSTQLGPAAGGTRAAQYSNLA
DALTDAGKLAGAMTLKMAVSNLPMGGGKSVIALPAPRHSIDPSTWARILR
IHAENIDKLSGNYWTGPDVNTNSADMDTLNDTTEFVFGRSLERGGAGSSA
FTTAVGVFEAMKATVAHRGLGSLDGLTVLVQGLGAVGGSLASLAAEAGAQ
LLVADTDTERVAHAVALGHTAVALEDVLSTPCDVFAPCAMGGVITTEVAR
TLDCSVVAGAANNVIADEAASDILHARGILYAPDFVANAGGAIHLVGREV
LGWSESVVHERAVAIGDTLNQVFEISDNDGVTPDEAARTLAGRRAREA
3D structure
PDB1c1x Rhodococcus L-phenylalanine dehydrogenase: kinetics, mechanism, and structural basis for catalytic specificity.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.4.1.20: phenylalanine dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HFA A G39 G40 M63 K66 F137 A292 L295 G39 G40 M63 K66 F137 A292 L295
BS02 NAD A S149 T153 G182 G184 A185 V186 D205 T206 R210 L224 C238 A239 M240 A260 N262 N288 S149 T153 G182 G184 A185 V186 D205 T206 R210 L224 C238 A239 M240 A260 N262 N288
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
GO:0050175 phenylalanine dehydrogenase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006559 L-phenylalanine catabolic process
GO:0009094 L-phenylalanine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1c1x, PDBe:1c1x, PDBj:1c1x
PDBsum1c1x
PubMed10924111
UniProtQ59771|DHPH_RHOSO Phenylalanine dehydrogenase (Gene Name=pdh)

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