Structure of PDB 1bui Chain A

Receptor sequence
>1buiA (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
PSFDCGKPQVEPKKCPGVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLIS
PEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTR
KDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGA
GLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGP
LVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
3D structure
PDB1bui The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action.
ChainA
Resolution2.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102 Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1) H59 D102 Q194 G195 D196 S197 G198
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0GJ A H57 D189 S190 C191 Q192 S195 S214 W215 G216 G219 H59 D191 S192 C193 Q194 S197 S216 W217 G218 G220
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1bui, PDBe:1bui, PDBj:1bui
PDBsum1bui
PubMed9783753
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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