Structure of PDB 1bt6 Chain A
Receptor sequence
>1bt6A (length=91) Species:
9606
(Homo sapiens) [
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PSQMEHAMETMMFTFHKFAGDKGYLTKEDLRVLMEKEFPGFLENQKDPLA
VDKIMKDLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMK
3D structure
PDB
1bt6
The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Chain
A
Resolution
2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
A
P1 E5 E9
P1 E5 E9
BS02
peptide
A
F41 N44 Q45 C82 Y85 M90
F41 N44 Q45 C82 Y85 M90
Gene Ontology
Molecular Function
GO:0005509
calcium ion binding
GO:0005515
protein binding
GO:0008289
lipid binding
GO:0042803
protein homodimerization activity
GO:0044325
transmembrane transporter binding
GO:0048306
calcium-dependent protein binding
Biological Process
GO:0001765
membrane raft assembly
GO:0006900
vesicle budding from membrane
GO:0010756
positive regulation of plasminogen activation
GO:0042789
mRNA transcription by RNA polymerase II
GO:0043547
positive regulation of GTPase activity
GO:0045921
positive regulation of exocytosis
GO:0045944
positive regulation of transcription by RNA polymerase II
GO:0050767
regulation of neurogenesis
GO:0051496
positive regulation of stress fiber assembly
GO:0051894
positive regulation of focal adhesion assembly
GO:0072659
protein localization to plasma membrane
GO:1900026
positive regulation of substrate adhesion-dependent cell spreading
GO:1905686
positive regulation of plasma membrane repair
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005737
cytoplasm
GO:0005886
plasma membrane
GO:0009986
cell surface
GO:0016363
nuclear matrix
GO:0045121
membrane raft
GO:0062023
collagen-containing extracellular matrix
GO:0070062
extracellular exosome
GO:0090575
RNA polymerase II transcription regulator complex
GO:0098797
plasma membrane protein complex
GO:1990665
AnxA2-p11 complex
View graph for
Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB
RCSB:1bt6
,
PDBe:1bt6
,
PDBj:1bt6
PDBsum
1bt6
PubMed
9886297
UniProt
P60903
|S10AA_HUMAN Protein S100-A10 (Gene Name=S100A10)
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