Structure of PDB 1bs2 Chain A

Receptor sequence
>1bs2A (length=603) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ANMISQLKKLSIAEPAVAKDSHPDVNIVDLMRNYISQELSKISGVDSSLI
FPALEWTNTMERGDLLIPIPRLRIKGANPKDLAVQWAEKFPCGDFLEKVE
ANGPFIQFFFNPQFLAKLVIPDILTRKEDYGSCKLVENKKVIIEFSSPNI
AKPFHAGHLRSTIIGGFLANLYEKLGWEVIRMNYLGDWGKQFGLLAVGFE
RYGNEEALVKDPIHHLFDVYVRINKDIEEEGDSIPLEQSTNGKAREYFKR
MEDGDEEALKIWKRFREFSIEKYIDTYARLNIKYDVYSGESQVSKESMLK
AIDLFKEKGLTHEDKGAVLIDLTKFNKKLGKAIVQKSDGTTLYLTRDVGA
AMDRYEKYHFDKMIYVIASQQDLHAAQFFEILKQMGFEWAKDLQHVNFGM
VQGMSTRKGTVVFLDNILEETKEKMHEVMKKNENKYAQIEHPEEVADLVG
ISAVMIQDMQGKRINNYEFKWERMLSFEGDTGPYLQYAHSRLRSVERNAS
GITQEKWINADFSLLKEPAAKLLIRLLGQYPDVLRNAIKTHEPTTVVTYL
FKLTHQVSSCYDVLWVAGQTEELATARLALYGAARQVLYNGMRLLGLTPV
ERM
3D structure
PDB1bs2 L-arginine recognition by yeast arginyl-tRNA synthetase.
ChainA
Resolution2.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K156 H159 H162
Catalytic site (residue number reindexed from 1) K152 H155 H158
Enzyme Commision number 6.1.1.19: arginine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ARG A E148 N153 H162 Y188 Y347 D351 Y369 E144 N149 H158 Y184 Y343 D347 Y365
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004814 arginine-tRNA ligase activity
GO:0005524 ATP binding
GO:1990825 sequence-specific mRNA binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006420 arginyl-tRNA aminoacylation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1bs2, PDBe:1bs2, PDBj:1bs2
PDBsum1bs2
PubMed9736621
UniProtQ05506|SYRC_YEAST Arginine--tRNA ligase, cytoplasmic (Gene Name=YDR341C)

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