Structure of PDB 1br2 Chain A

Receptor sequence
>1br2A (length=673) Species: 9031 (Gallus gallus) [Search protein sequence]
LVWVPSEKHGFEAASIEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDM
AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIID
MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK
VIQYLAVVASGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFD
VTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLL
EGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVS
SVLQLGNIVFKKEQASMPDNTAAQKVCHLMGINVTDFTRSILTPKAQTKE
QADFAIEALAKAKFERLFRWILTRVNKALDASFLGILDIAGFEIFEINSF
EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIEL
IERPTNPPGVLALLDEECATDTSFVEKLIQEQGNHAKFQKSKTEFCILHY
AGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKRTVGQLYKEQ
LTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRI
CRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNL
YRIGQSKIFFRTGVLAHLEEERD
3D structure
PDB1br2 Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
ChainA
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S179 G180 T184 N242 S245 S246 G468 E470
Catalytic site (residue number reindexed from 1) S140 G141 T145 N185 S188 S189 G391 E393
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T184 S246 D465 T145 S189 D388
BS02 ALF A S179 K183 S245 S246 G468 S140 K144 S188 S189 G391
BS03 ADP A N125 P126 Y127 Y133 G180 G182 K183 T184 E185 N242 N86 P87 Y88 Y94 G141 G143 K144 T145 E146 N185
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1br2, PDBe:1br2, PDBj:1br2
PDBsum1br2
PubMed9741621
UniProtP10587|MYH11_CHICK Myosin-11 (Gene Name=MYH11)

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