Structure of PDB 1bqi Chain A

Receptor sequence
>1bqiA (length=212) Species: 3649 (Carica papaya) [Search protein sequence]
IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSE
QELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREK
GPYAAKTDGVRQVQPYNQGALLYSIANQPVSVVLQAAGKDFQLYRGGIFV
GPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVC
GLYTSSFYPVKN
3D structure
PDB1bqi Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) V16 Q19 C25 N155 H159 N175
Catalytic site (residue number reindexed from 1) V16 Q19 C25 N155 H159 N175
Enzyme Commision number 3.4.22.2: papain.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SBA A Q142 W177 G180 W181 Q142 W177 G180 W181
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1bqi, PDBe:1bqi, PDBj:1bqi
PDBsum1bqi
PubMed9804696
UniProtP00784|PAPA1_CARPA Papain

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