Structure of PDB 1bnk Chain A

Receptor sequence
>1bnkA (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]
KGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIVETEAYLG
PEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACV
LLRALEPLEGLETMRQLRSRVLKDRELCSGPSKLCQALAINKSFDQRDLA
QDEAVWLERAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQD
3D structure
PDB1bnk Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.21: DNA-3-methyladenine glycosylase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H136 Y159 Y162 Y165 R201 G217 P218 S219 K220 G263 H266 H57 Y80 Y83 Y86 R118 G130 P131 S132 K133 G168 H171
BS02 dna A R141 T143 R145 Y162 M164 R62 T64 R66 Y83 M85
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003905 alkylbase DNA N-glycosylase activity
Biological Process
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1bnk, PDBe:1bnk, PDBj:1bnk
PDBsum1bnk
PubMed9790531
UniProtP29372|3MG_HUMAN DNA-3-methyladenine glycosylase (Gene Name=MPG)

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