Structure of PDB 1bmt Chain A

Receptor sequence
>1bmtA (length=246) Species: 562 (Escherichia coli) [Search protein sequence]
QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDG
MNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGKTNGKMV
IATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADL
IGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNY
SGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGR
3D structure
PDB1bmt How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase.
ChainA
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D757 H759 S810
Catalytic site (residue number reindexed from 1) D107 H109 S160
Enzyme Commision number 2.1.1.13: methionine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COB A E694 M698 M701 G705 L715 V718 D757 V758 H759 D760 I761 I765 G802 L803 S804 L806 I807 T808 G833 G834 A835 V857 N859 A860 E44 M48 M51 G55 L65 V68 D107 V108 H109 D110 I111 I115 G152 L153 S154 L156 I157 T158 G183 G184 A185 V207 N209 A210
Gene Ontology
Molecular Function
GO:0031419 cobalamin binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1bmt, PDBe:1bmt, PDBj:1bmt
PDBsum1bmt
PubMed7992050
UniProtP13009|METH_ECOLI Methionine synthase (Gene Name=metH)

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