Structure of PDB 1bmb Chain A

Receptor sequence
>1bmbA (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDV
QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
3D structure
PDB1bmb Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R67 R86 S88 S90 S96 H107 F108 K109 L120 W121 R12 R31 S33 S35 S41 H52 F53 K54 L65 W66
External links
PDB RCSB:1bmb, PDBe:1bmb, PDBj:1bmb
PDBsum1bmb
PubMed10090780
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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