Structure of PDB 1bbz Chain A

Receptor sequence
>1bbzA (length=58) Species: 9606 (Homo sapiens) [Search protein sequence]
NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPS
NYITPVNS
3D structure
PDB1bbz Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 D14 E35 W36 W47 P49 Y52 Y7 D14 E35 W36 W47 P49 Y52
BS02 peptide A F3 L6 Y30 G34 S50 N51 I53 T54 P55 S58 F3 L6 Y30 G34 S50 N51 I53 T54 P55 S58
External links
PDB RCSB:1bbz, PDBe:1bbz, PDBj:1bbz
PDBsum1bbz
PubMed9698566
UniProtP00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)

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