Structure of PDB 1b4q Chain A

Receptor sequence
>1b4qA (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
AQEFVNSKIQPGKVVVFIKPTCPYSRRAQEILSQLPIKQGLLEFVDITAT
NHTNEIQDYLQQLTGARTVPRVFIGKDSIGGSSDLVSLQQSGELLTRLKQ
IGALQ
3D structure
PDB1b4q Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A C22 Y24 R67 T68 V69 G81 S82 S83 C22 Y24 R67 T68 V69 G81 S82 S83
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0017080 sodium channel regulator activity
Biological Process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0045838 positive regulation of membrane potential
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1b4q, PDBe:1b4q, PDBj:1b4q
PDBsum1b4q
PubMed9860827
UniProtP35754|GLRX1_HUMAN Glutaredoxin-1 (Gene Name=GLRX)

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