Structure of PDB 1ayc Chain A

Receptor sequence
>1aycA (length=100) Species: 10090 (Mus musculus) [Search protein sequence]
RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTH
IKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN
3D structure
PDB1ayc Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R32 S34 K35 S36 T42 T52 H53 I54 K55 L65 E90 R29 S31 K32 S33 T39 T49 H50 I51 K52 L62 E87
External links
PDB RCSB:1ayc, PDBe:1ayc, PDBj:1ayc
PDBsum1ayc
PubMed7521735
UniProtP35235|PTN11_MOUSE Tyrosine-protein phosphatase non-receptor type 11 (Gene Name=Ptpn11)

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