Structure of PDB 1ayb Chain A

Receptor sequence
>1aybA (length=100) Species: 10090 (Mus musculus) [Search protein sequence]
RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTH
IKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN
3D structure
PDB1ayb Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R32 S34 K35 S36 T42 V51 T52 H53 K55 G67 G68 K89 K91 R29 S31 K32 S33 T39 V48 T49 H50 K52 G64 G65 K86 K88
External links
PDB RCSB:1ayb, PDBe:1ayb, PDBj:1ayb
PDBsum1ayb
PubMed7521735
UniProtP35235|PTN11_MOUSE Tyrosine-protein phosphatase non-receptor type 11 (Gene Name=Ptpn11)

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