Structure of PDB 1awc Chain A

Receptor sequence
>1awcA (length=110) Species: 10090 (Mus musculus) [Search protein sequence]
IQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTM
NYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVI
ECEQKKLARM
3D structure
PDB1awc The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y371 R376 R379 Y380 Y382 K389 R394 F395 Y52 R57 R60 Y61 Y63 K70 R75 F76
BS02 dna A Q321 W360 K364 M369 K373 R376 Y380 Y381 Q2 W41 K45 M50 K54 R57 Y61 Y62
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:1awc, PDBe:1awc, PDBj:1awc
PDBsum1awc
PubMed9461436
UniProtQ00422|GABPA_MOUSE GA-binding protein alpha chain (Gene Name=Gabpa)

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