Structure of PDB 1avp Chain A

Receptor sequence
>1avpA (length=204) Species: 10515 (Human adenovirus 2) [Search protein sequence]
MGSSEQELKAIVKDLGCGPYFLGTYDKRFPGFVSPHKLACAIVNTAGRET
GGVHWMAFAWNPRSKTCYLFEPFGFSDQRLKQVYQFEYESLLRRSAIASS
PDRCITLEKSTQSVQGPNSAACGLFCCMFLHAFANWPQTPMDHNPTMNLI
TGVPNSMLNSPQVQPTLRRNQEQLYSFLERHSPYFRSHSAQIRSATSFCH
LKNM
3D structure
PDB1avp Crystal structure of the human adenovirus proteinase with its 11 amino acid cofactor.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H54 E71 Q115 C122
Catalytic site (residue number reindexed from 1) H54 E71 Q115 C122
Enzyme Commision number 3.4.22.39: adenain.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D77 R93 R103 C104 I105 T106 L107 E108 K109 S110 T111 Q112 M141 D142 M147 I150 G152 D77 R93 R103 C104 I105 T106 L107 E108 K109 S110 T111 Q112 M141 D142 M147 I150 G152
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1avp, PDBe:1avp, PDBj:1avp
PDBsum1avp
PubMed8617222
UniProtP03252|PRO_ADE02 Protease (Gene Name=L3)

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