Structure of PDB 1aqc Chain A

Receptor sequence
>1aqcA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
MEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLMT
EVDLFILTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRYKM
ICHVFESEDAQLIAQSIGQAFSVAYQEFLR
3D structure
PDB1aqc Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R353 R414 I416 S417 Y418 I419 A420 R431 M458 A472 Q473 F479 Y483 F486 R31 R78 I80 S81 Y82 I83 A84 R95 M100 A114 Q115 F121 Y125 F128
External links
PDB RCSB:1aqc, PDBe:1aqc, PDBj:1aqc
PDBsum1aqc
PubMed9321393
UniProtQ02410|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding family A member 1 (Gene Name=APBA1)

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