Structure of PDB 1ala Chain A

Receptor sequence
>1alaA (length=316) Species: 9031 (Gallus gallus) [Search protein sequence]
KYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQE
IASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKG
AGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRL
LVVLLQANRDPDGRVEEALVEKDAQVLFRAGELKWGTDEETFITILGTRS
VSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFA
ETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQK
DTSGDYRKALLLLCGG
3D structure
PDB1ala Structure of chicken annexin V at 2.25-A resolution.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A M28 G30 G32 E72 M26 G28 G30 E70
BS02 CA A I100 K101 G102 G104 E144 I98 K99 G100 G102 E142
BS03 CA A M259 G261 G263 D303 M257 G259 G261 D301
Gene Ontology
Molecular Function
GO:0001786 phosphatidylserine binding
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0050819 negative regulation of coagulation
GO:0055074 calcium ion homeostasis
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0012506 vesicle membrane
GO:0031982 vesicle
GO:0034704 calcium channel complex
GO:0042383 sarcolemma

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ala, PDBe:1ala, PDBj:1ala
PDBsum1ala
PubMed8471604
UniProtP17153|ANXA5_CHICK Annexin A5 (Gene Name=ANXA5)

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