Structure of PDB 1al7 Chain A

Receptor sequence
>1al7A (length=350) Species: 3562 (Spinacia oleracea) [Search protein sequence]
MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPR
ILIDVTNIDMTTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAG
TIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAERAGFK
AIALTVDTPRLGRREADIKNRFVLPPFLTLKNFEGIDLGLSSYVAGQIDR
SLSWKDVAWLQTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGARQL
DYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVFIGR
PVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWD
3D structure
PDB1al7 Three-dimensional structures of glycolate oxidase with bound active-site inhibitors.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S106 Y129 T155 D157 K230 H254
Catalytic site (residue number reindexed from 1) S106 Y129 T155 D157 K221 H245
Enzyme Commision number 1.1.3.15: (S)-2-hydroxy-acid oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A Y24 Y25 P77 T78 A79 S106 Q127 T155 K230 H254 R257 D285 G286 R289 G308 R309 Y24 Y25 P77 T78 A79 S106 Q127 T155 K221 H245 R248 D276 G277 R280 G299 R300
BS02 HST A Y24 W108 Y129 R164 F172 I207 H254 R257 Y24 W108 Y129 R164 F172 I198 H245 R248 PDBbind-CN: -logKd/Ki=7.80,Ki=16nM
Gene Ontology
Molecular Function
GO:0003973 (S)-2-hydroxy-acid oxidase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0009853 photorespiration
GO:0009854 oxidative photosynthetic carbon pathway
GO:0051707 response to other organism
Cellular Component
GO:0005777 peroxisome

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Cellular Component
External links
PDB RCSB:1al7, PDBe:1al7, PDBj:1al7
PDBsum1al7
PubMed9144771
UniProtP05414|GOX_SPIOL Glycolate oxidase

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