Structure of PDB 1ais Chain A

Receptor sequence
>1aisA (length=181) Species: 2262 (Pyrococcus woesei) [Search protein sequence]
MVDMSKVKLRIENIVASVDLFAQLDLEKVLDLCPNSKYNPEEFPGIICHL
DDPKVALLIFSSGKLVVTGAKSVQDIERAVAKLAQKLKSIGVKFKRAPQI
DVQNMVFSGDIGREFNLDVVALTLPNCEYEPEQFPGVIYRVKEPKSVILL
FSSGKIVCSGAKSEADAWEAVRKLLRELDKY
3D structure
PDB1ais The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A V15 P44 F60 S62 V66 Q103 N104 F134 R140 V147 S159 V15 P44 F60 S62 V66 Q103 N104 F134 R140 V147 S159
BS02 dna A E12 N13 E42 F43 H49 L58 T68 V106 P135 F151 S153 K155 V157 E12 N13 E42 F43 H49 L58 T68 V106 P135 F151 S153 K155 V157
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0140223 general transcription initiation factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1ais, PDBe:1ais, PDBj:1ais
PDBsum1ais
PubMed9177165
UniProtP62001|TBP_PYRWO TATA-box-binding protein (Gene Name=tbp)

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